Food supplementation among HIV-infected adults in Sub-Saharan Africa: impact on treatment adherence and weight gain.
Identifieur interne : 000340 ( Main/Exploration ); précédent : 000339; suivant : 000341Food supplementation among HIV-infected adults in Sub-Saharan Africa: impact on treatment adherence and weight gain.
Auteurs : Keiron A. Audain [Afrique du Sud] ; Francis B. Zotor [Ghana] ; Paul Amuna [Royaume-Uni] ; Basma Ellahi [Royaume-Uni]Source :
- The Proceedings of the Nutrition Society [ 1475-2719 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte, Afrique subsaharienne, Agents antiVIH (usage thérapeutique), Aliment enrichi, Approvisionnement en nourriture, Compléments alimentaires, Humains, Indice de masse corporelle, Infections à VIH (), Infections à VIH (traitement médicamenteux), Malnutrition (), Micronutriments (administration et posologie), Observance du traitement médicamenteux, Prise de poids, Régime alimentaire, Évaluation de résultat (soins).
- MESH :
- administration et posologie : Micronutriments.
- traitement médicamenteux : Infections à VIH.
- usage thérapeutique : Agents antiVIH.
- Adulte, Afrique subsaharienne, Aliment enrichi, Approvisionnement en nourriture, Compléments alimentaires, Humains, Indice de masse corporelle, Infections à VIH, Malnutrition, Observance du traitement médicamenteux, Prise de poids, Régime alimentaire, Évaluation de résultat (soins).
English descriptors
- KwdEn :
- Adult, Africa South of the Sahara, Anti-HIV Agents (therapeutic use), Body Mass Index, Diet, Dietary Supplements, Food Supply, Food, Fortified, HIV Infections (complications), HIV Infections (drug therapy), Humans, Malnutrition (complications), Malnutrition (prevention & control), Medication Adherence, Micronutrients (administration & dosage), Outcome Assessment (Health Care), Weight Gain.
- MESH :
- chemical , administration & dosage : Micronutrients.
- chemical , therapeutic use : Anti-HIV Agents.
- geographic : Africa South of the Sahara.
- complications : HIV Infections, Malnutrition.
- drug therapy : HIV Infections.
- prevention & control : Malnutrition.
- Adult, Body Mass Index, Diet, Dietary Supplements, Food Supply, Food, Fortified, Humans, Medication Adherence, Outcome Assessment (Health Care), Weight Gain.
Abstract
Sub-Saharan Africa has the highest proportion of undernourished people in the world, along with the highest number of people living with HIV and AIDS. Thus, as a result of high levels of food insecurity many HIV patients are also undernourished. The synergism between HIV and undernutrition leads to poor treatment adherence and high mortality rates. Undernutrition has a debilitating effect on the immune system due to key nutrient deficiencies and the overproduction of reactive species (oxidative stress), which causes rapid HIV progression and the onset of AIDS. Therapeutic food supplementation used in the treatment of severe acute malnutrition is being applied to HIV palliative care; however, little biochemical data exist to highlight its impact on oxidative stress and immune recovery. In addition, as most food supplements are imported by donor agencies, efforts are being put into local therapeutic food production such as the Food Multi-Mix concept to ensure sustainability. The purpose of this review is to highlight studies that examine the effectiveness of food supplementation in undernourished HIV patients in Sub-Saharan Africa; noting the parameters used to measure efficacy, as well as the long-term feasibility of supplementation.
DOI: 10.1017/S0029665115000063
PubMed: 25761769
Affiliations:
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Audain</name><affiliation wicri:level="1"><nlm:affiliation>Dietetics and Human Nutrition,College of Science and Agriculture,University of KwaZulu Natal,Pietermaritzburg3209,South Africa.</nlm:affiliation><country xml:lang="fr">Afrique du Sud</country><wicri:regionArea>Dietetics and Human Nutrition,College of Science and Agriculture,University of KwaZulu Natal,Pietermaritzburg3209</wicri:regionArea><wicri:noRegion>Pietermaritzburg3209</wicri:noRegion></affiliation></author><author><name sortKey="Zotor, Francis B" sort="Zotor, Francis B" uniqKey="Zotor F" first="Francis B" last="Zotor">Francis B. Zotor</name><affiliation wicri:level="1"><nlm:affiliation>School of Public Health,University of Health and Allied Sciences,Hohoe,Ghana.</nlm:affiliation><country xml:lang="fr">Ghana</country><wicri:regionArea>School of Public Health,University of Health and Allied Sciences,Hohoe</wicri:regionArea><wicri:noRegion>Hohoe</wicri:noRegion></affiliation></author><author><name sortKey="Amuna, Paul" sort="Amuna, Paul" uniqKey="Amuna P" first="Paul" last="Amuna">Paul Amuna</name><affiliation wicri:level="1"><nlm:affiliation>Department of Life Sciences,University of Greenwich,Medway,Kent,UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Life Sciences,University of Greenwich,Medway,Kent</wicri:regionArea><wicri:noRegion>Kent</wicri:noRegion></affiliation></author><author><name sortKey="Ellahi, Basma" sort="Ellahi, Basma" uniqKey="Ellahi B" first="Basma" last="Ellahi">Basma Ellahi</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health and Social Care,University of Chester,Chester,UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Faculty of Health and Social Care,University of Chester,Chester</wicri:regionArea><wicri:noRegion>Chester</wicri:noRegion></affiliation></author></analytic><series><title level="j">The Proceedings of the Nutrition Society</title><idno type="eISSN">1475-2719</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Africa South of the Sahara</term><term>Anti-HIV Agents (therapeutic use)</term><term>Body Mass Index</term><term>Diet</term><term>Dietary Supplements</term><term>Food Supply</term><term>Food, Fortified</term><term>HIV Infections (complications)</term><term>HIV Infections (drug therapy)</term><term>Humans</term><term>Malnutrition (complications)</term><term>Malnutrition (prevention & control)</term><term>Medication Adherence</term><term>Micronutrients (administration & dosage)</term><term>Outcome Assessment (Health Care)</term><term>Weight Gain</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Afrique subsaharienne</term><term>Agents antiVIH (usage thérapeutique)</term><term>Aliment enrichi</term><term>Approvisionnement en nourriture</term><term>Compléments alimentaires</term><term>Humains</term><term>Indice de masse corporelle</term><term>Infections à VIH ()</term><term>Infections à VIH (traitement médicamenteux)</term><term>Malnutrition ()</term><term>Micronutriments (administration et posologie)</term><term>Observance du traitement médicamenteux</term><term>Prise de poids</term><term>Régime alimentaire</term><term>Évaluation de résultat (soins)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Micronutrients</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Anti-HIV Agents</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Africa South of the Sahara</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Micronutriments</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>HIV Infections</term><term>Malnutrition</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>HIV Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Malnutrition</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à VIH</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Agents antiVIH</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Body Mass Index</term><term>Diet</term><term>Dietary Supplements</term><term>Food Supply</term><term>Food, Fortified</term><term>Humans</term><term>Medication Adherence</term><term>Outcome Assessment (Health Care)</term><term>Weight Gain</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Afrique subsaharienne</term><term>Aliment enrichi</term><term>Approvisionnement en nourriture</term><term>Compléments alimentaires</term><term>Humains</term><term>Indice de masse corporelle</term><term>Infections à VIH</term><term>Malnutrition</term><term>Observance du traitement médicamenteux</term><term>Prise de poids</term><term>Régime alimentaire</term><term>Évaluation de résultat (soins)</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sub-Saharan Africa has the highest proportion of undernourished people in the world, along with the highest number of people living with HIV and AIDS. Thus, as a result of high levels of food insecurity many HIV patients are also undernourished. The synergism between HIV and undernutrition leads to poor treatment adherence and high mortality rates. Undernutrition has a debilitating effect on the immune system due to key nutrient deficiencies and the overproduction of reactive species (oxidative stress), which causes rapid HIV progression and the onset of AIDS. Therapeutic food supplementation used in the treatment of severe acute malnutrition is being applied to HIV palliative care; however, little biochemical data exist to highlight its impact on oxidative stress and immune recovery. In addition, as most food supplements are imported by donor agencies, efforts are being put into local therapeutic food production such as the Food Multi-Mix concept to ensure sustainability. The purpose of this review is to highlight studies that examine the effectiveness of food supplementation in undernourished HIV patients in Sub-Saharan Africa; noting the parameters used to measure efficacy, as well as the long-term feasibility of supplementation.</div></front></TEI><affiliations><list><country><li>Afrique du Sud</li><li>Ghana</li><li>Royaume-Uni</li></country></list><tree><country name="Afrique du Sud"><noRegion><name sortKey="Audain, Keiron A" sort="Audain, Keiron A" uniqKey="Audain K" first="Keiron A" last="Audain">Keiron A. Audain</name></noRegion></country><country name="Ghana"><noRegion><name sortKey="Zotor, Francis B" sort="Zotor, Francis B" uniqKey="Zotor F" first="Francis B" last="Zotor">Francis B. Zotor</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Amuna, Paul" sort="Amuna, Paul" uniqKey="Amuna P" first="Paul" last="Amuna">Paul Amuna</name></noRegion><name sortKey="Ellahi, Basma" sort="Ellahi, Basma" uniqKey="Ellahi B" first="Basma" last="Ellahi">Basma Ellahi</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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